Tuesday, November 8, 2011

Patrick will run 10 Cup races, debut at Daytona

Danica Patrick poses with a tribute helmet to Daniel Wheldon after a media availability at Texas Motor Speedway in Fort Worth, Texas, Friday, Nov. 4, 2011. Patrick, who is moving full time to NASCAR next season, is racing Saturday for the first time since the IndyCar Series finale at Las Vegas three weeks ago. (AP Photo/LM Otero)

Danica Patrick poses with a tribute helmet to Daniel Wheldon after a media availability at Texas Motor Speedway in Fort Worth, Texas, Friday, Nov. 4, 2011. Patrick, who is moving full time to NASCAR next season, is racing Saturday for the first time since the IndyCar Series finale at Las Vegas three weeks ago. (AP Photo/LM Otero)

Danica Patrick, left, and Tony Stewart pose with the No. 10 car at its unveiling at Texas Motor Speedway, Friday, Nov. 4, 2011, in Fort Worth, Texas. Patrick, who is moving full time to NASCAR next season, is racing Saturday for the first time since the IndyCar Series finale at Las Vegas three weeks ago. (AP Photo/LM Otero)

Danica Patrick, left, and Tony Stewart joke around in front of the No. 10 car at its unveiling at Texas Motor Speedway, Friday, Nov. 4, 2011, in Fort Worth, Texas. Patrick, who is moving full time to NASCAR next season, is racing Saturday for the first time since the IndyCar Series finale at Las Vegas three weeks ago. (AP Photo/LM Otero)

(AP) ? Danica Patrick will make her Sprint Cup debut in the season-opening Daytona 500 in February, her first of 10 races in NASCAR's highest division for Stewart-Haas Racing next season.

Her limited Cup schedule and Patrick's new green No. 10 GoDaddy.com Chevrolet were unveiled Friday at Texas.

Team co-owner Tony Stewart said the team is set on eight of Patrick's 10 races. Her second scheduled race will be May 12 at Darlington, with the other six already set coming late in the season ? at Bristol, Atlanta, Chicagoland, Dover, Texas and Phoenix.

"The big thing is just keeping in mind it's a learning year next year," Stewart said. "It's an aggressive schedule and an ambition one for somebody that hasn't been in a Cup car yet, but at the same time, to compete at this level, you're going to have to be good at these tracks."

Stewart said the particular races were picked as part of the learning curve.

The determination on the other two races will be made based on what kind of progress Patrick makes and if there is particular venue or style of track where more laps would be beneficial.

Patrick also will run a full Nationwide Series schedule for JR Motorsports in her transition from IndyCar to NASCAR full time.

The plan is for Patrick possibly being ready to run the full Cup schedule in 2013.

"I'm excited. There's a lot I'm worried for, but on the other hand, as I've kind of felt with my Nationwide races ... (at) more difficult tracks expectation levels sometimes are not quite as high and you have the ability to make mistakes," she said. "That's the plan. There's going to be mistakes and there's going to be learning curves, and get that out of the way before we try and do this full time and really try and put it together."

Stewart expressed confidence about Patrick making her Cup debut at Daytona based on the Nationwide Series race there in July, when she finished 10th, three spots ahead of him.

"Daytona is a very cool place. You can definitely feel the history," Patrick said, before looking to her right at Stewart. "It's definitely a different kind of racing. It's lot of fun, especially when you have a good partner."

The No. 10 has some personal significance to Patrick. It was the number she had in go-karts when she first got into racing, and this is the first time she has been able to use that number as a professional driver.

That selection coincides with her Cup teammates, whose current car numbers are also the same ones they used at the start of their racing careers. Tony Stewart had the No. 14 in go-karts and Ryan Newman was No. 39 in quarter midgets.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2011-11-04-NASCAR-Patrick%20Plans/id-4b402ae998634684a7b694a00a872f6f

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Monday, November 7, 2011

New Nook Tablet Specs Aimed at Hosing Kindle Fire (NewsFactor)

Barnes & Noble will release a Nook Tablet on Monday that has twice the memory and storage of Amazon's coming Kindle Fire, according to new reports on the Web. The new tablet will be offered at $249, currently the price of the Nook Color, which is expected to drop in price below $200.

The new tablet could point to the further evolution of e-readers into mini-tablets. The Nook Tablet can build on the success of the Nook Color, which is now second in shipments to Apple's iPad 2.

Nov. 15 and 16

The Kindle Fire ships Nov. 15, and, according to the reports, the new Nook Tablet will ship the next day. The Nook Tablet will feature 1 GB of memory, compared with 512 MB for the Color and the Fire. It will also have 16 GB of storage, expandable to 32 GB, and will sport a 1.2 GHz dual-core processor, faster than the dual-core in the Fire and the single-core in the Color. The Color and the Fire each have 8 GB of storage.

Several weeks ago, Amazon unveiled its Kindle Fire tablet, which will sell for $199. Aside from the price and hardware differences, the Fire takes advantage of Amazon's cloud to speed up Web browsing, and is intended to be a playback device for Amazon's huge store of content. According to news reports, Amazon is selling the Kindle as a loss leader, under the price of manufacture, in order to move more content.

Amazon has also been actively working to build on its content advantage. On Thursday, it announced the Kindle Owners Lending Library, with thousands of book titles -- including more than 100 bestsellers -- available at no additional charge to Kindle-owning subscribers of Amazon Prime, which costs $79 annually and includes other benefits. Recently, the company also announced an arrangement with about 11,000 public libraries to offer free lending copies of e-books for the Kindle device.

In an interview with Bloomberg News Service, Amazon founder and head Jeff Bezos has said that his company doesn't "think of the Kindle Fire as a tablet. We think of it as a service."

B&N 'Doesn't Have a Choice'

Avi Greengart, an analyst with industry research firm Current Analysis, noted that the Nook Color "is due for a refresh," which the Nook Tablet will provide. But it's clear, he said, that Barnes & Noble, like Amazon, wants to attract third-party application developers to its platform and continue the transition from e-readers to mini-tablets.

Greengart noted that Barnes & Noble has done "some interesting things in using its brick-and-mortar stores in conjunction with its tablets," such as in-store offers. But, he said, Amazon's huge content inventory is "way more" than just books, with audio books, movies, music, TV shows, apps, and physical goods, plus cloud-based storage and computing power to speed Web browsing.

This is a formidable challenge to Barnes & Noble, Greengart said, but the retailer "doesn't have a choice," since the book business is going digital.

"They've done a pretty good job so far," he added, "but they might be outgunned going forward."

Source: http://us.rd.yahoo.com/dailynews/rss/personaltech/*http%3A//news.yahoo.com/s/nf/20111104/bs_nf/80883

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Sunday, November 6, 2011

Brain parasite directly alters brain chemistry

Friday, November 4, 2011

A research group from the University of Leeds has shown that infection by the brain parasite Toxoplasma gondii, found in 10-20 per cent of the UK's population, directly affects the production of dopamine, a key chemical messenger in the brain.

Their findings are the first to demonstrate that a parasite found in the brain of mammals can affect dopamine levels.

Whilst the work has been carried out with rodents, lead investigator Dr Glenn McConkey of the University's Faculty of Biological Sciences, believes that the findings could ultimately shed new light on treating human neurological disorders that are dopamine-related such as schizophrenia, attention deficit hyperactivity disorder, and Parkinson's disease.

This research may explain how these parasites, remarkably, manipulate rodents' behaviour for their own advantage. Infected mice and rats lose their innate fear of cats, increasing the chances of being caught and eaten, which enables the parasite to return to its main host to complete its life cycle.

In this study, funded by the Stanley Medical Research Institute and Dunhill Medical Trust, the research team found that the parasite causes production and release of many times the normal amount of dopamine in infected brain cells.

Dopamine is a natural chemical which relays messages in the brain controlling aspects of movement, cognition and behaviour. It helps control the brain's reward and pleasure centres and regulates emotional responses such as fear. The presence of a certain kind of dopamine receptor is also associated with sensation-seeking, whereas dopamine deficiency in humans results in Parkinson's disease.

These findings build on earlier studies in which Dr McConkey's group found that the parasite actually encodes the enzyme for producing dopamine in its genome.

"Based on these analyses, it was clear that T. gondii can orchestrate a significant increase in dopamine production in neural cells," says Dr McConkey.

"Humans are accidental hosts to T. gondii and the parasite could end up anywhere in the brain, so human symptoms of toxoplasmosis infection may depend on where parasite ends up. This may explain the observed statistical link between incidences of schizophrenia and toxoplasmosis infection."

Dr McConkey says his next experiments will investigate how the parasite enzyme triggers dopamine production and how this may change behaviour.

###

University of Leeds: http://www.leeds.ac.uk

Thanks to University of Leeds for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/114964/Brain_parasite_directly_alters_brain_chemistry

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King not buying reports on Cain (Politico)

POLITICO's Jake Sherman reports from the Hill:

Iowa Rep. Steve King said the women who accused Herman Cain of sexual harassment are likely ?liberal activists? and ?official hyperventilaters of the first order.?

In a brief interview with POLITICO Thursday, King said news outlets were wrong to report on the story.

Continue Reading

?I think that unless we have one, two or three Anita Hills stand up and say ?this is what I say he did,? then it should?ve never been a story,? King said. ?What are we talking about? We?re talking about a story about a story, we don?t know what the story is, we don?t know what the allegations are.?

King has not endorsed a candidate.

Source: http://us.rd.yahoo.com/dailynews/rss/politics/*http%3A//us.rd.yahoo.com/dailynews/external/politico_rss/rss_politico_mostpop/http___www_politico_com_news_stories1111_67588_html/43490879/SIG=11mcebakg/*http%3A//www.politico.com/news/stories/1111/67588.html

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Too posh to push? More C-sections on demand in UK

(AP) ? Pregnant women in Britain, where the government provides free health care, may soon be able to get a cesarean section on demand thanks to a rule change that critics describe as the health system caving into the "too posh to push" crowd.

Currently, British women who can't afford to pay private doctors for their baby's delivery have been allowed to have planned C-sections only if there are health concerns for mother or baby. Emergency C-sections are done when the situation demands it.

But new guidelines set to take effect later this month say pregnant women "with no identifiable reason" should be allowed a cesarean if they still want it following a discussion with mental health experts.

"It's about time women who have no desire to view labor as a rite of passage into motherhood be able to choose how they want to have their baby," said Pauline Hull, who has had two children by cesarean because of medical reasons. "The important thing to me was meeting my baby, not the experience of labor."

Hull runs a website about elective C-sections from her home in Surrey, south of London. She said doctors tend to overexaggerate the risks of C-sections and underestimate those of vaginal births.

The new draft guidelines come from the National Institute for Health and Clinical Excellence, or NICE. The agency's guidelines are usually accepted by the government and determine what will be paid for by its health system.

"In general, a C-section is a safe operation, especially when performed as a planned procedure," the new guidance says.

The agency says it routinely updates guidance every few years and denies there was any pressure to change its more restrictive C-section advice. But in recent years, advocates and some doctors have slammed the U.K. health system for not giving women a greater say in childbirth.

The change comes at a price for Britain's cash-strapped health system. NICE estimates C-sections cost about 800 pounds ($1,280) more than a vaginal birth, although that doesn't include the price of treating possible long-term complications like urinary incontinence from vaginal births.

The report notes that for every percentage point the C-section rate falls, the health system could save 5.6 billion pounds ($8.9 billion).

In the U.K., about 25 percent of women have C-sections, versus about 30 percent in the U.S. In both countries, rates have doubled in recent years, though doctors say that's not just due to demand, but because pregnant women increasingly have other problems like obesity and diabetes.

About 10 percent of all U.K. births are planned C-sections while about 15 percent are emergency procedures, according to NHS figures.

The World Health Organization says wealthy countries should aim for a C-section rate of about 15 percent.

The National Health Service estimates that about 15 percent of British births take place in private hospitals, which tend to have higher cesarean rates. At Portland Hospital in London, where many celebrities check in, the C-section rate ranges from 35 to 40 percent.

The issue of women having C-sections on demand has long been a hot button issue in the U.K., with celebrities like Madonna and former Spice Girl Victoria Beckham having scheduled procedures at upscale hospitals. Criticism for the wealthy getting these elective surgeries led to the phrase "too posh to push."

But some experts say the new British guidance won't dramatically change how pregnant women are treated.

"It's only a small percentage of women who ask for a C-section," said Cathy Warwick, chief executive of the Royal College of Midwives.

Warwick said doctors and midwives regularly talk to women who have concerns about childbirth and after addressing their fears, most women agree to skip a planned C-section.

"As long as it's safe for both mother and baby, a vaginal birth is absolutely the best way for anyone to deliver," said Dr. Daghni Rajasingham, an obstetrician and spokeswoman for the Royal College of Obstetricians and Gynaecologists. She said the physical stress put on a baby's lungs during labor helps them adapt to breathing after being born.

Rajasingham also said while C-sections are safe, the operation comes with risks including infections, bleeding, and the potential for problems with future pregnancies.

"As an obstetrician working with limited resources, I want to make sure we have safe and high-quality health care for all women and not be skewed by a few women who want something specifically," Rajasingham said.

For women like Hull, however, the policy shift is long overdue.

"Women shouldn't think a C-section is going to be a walk in the park, but they should have all the information they need to help them make an informed choice," she said.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/bbd825583c8542898e6fa7d440b9febc/Article_2011-11-04-EU-MED-C-Section-Guidelines/id-01a65565559748b695f3354d7d5cfa20

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Saturday, November 5, 2011

Sneak a little science in: blogs in teaching


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I have been traveling and speaking a lot this semester, perhaps too much. Because we?ve both had so many traveling commitments this year, for the last month I?ve hardly seen my husband, because he?s away one week and I?m away the next. But a few of my speaking engagements have been on campus, which certainly makes things easier.

The talk I?m about to share is is on blogging and teaching, for a campus brown bag series on technology in teaching here at the University of Illinois. This is the first time I?ve ever given a talk on pedagogy instead of research, and it was quite fun. I got to talk about blogging, about the many things I?ve tried that totally failed in the beginning, and what seems to have gone well to help me ?sneak a little science in? for the non-science majors that I mostly teach. The attendees had great questions at the end and it was a good conversation.

And of course, in the spirit of appreciating technology in teaching, the folks who convened the brown bag recorded the talk. Enjoy!

Kate ClancyAbout the Author: Dr. Kate Clancy is an Assistant Professor of Anthropology at the University of Illinois. She studies the evolutionary medicine of women?s reproductive physiology, and blogs about her field, the evolution of human behavior and issues for women in science. Follow on Twitter @KateClancy.

The views expressed are those of the author and are not necessarily those of Scientific American.

Source: http://rss.sciam.com/click.phdo?i=344b731314a08864a24592a326b3a3a8

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A Brief Guide to Embodied Cognition: Why You Are Not Your Brain

Embodied cognition, the idea that the mind is not only connected to the body but that the body influences the mind, is one of the more counter-intuitive ideas in cognitive science. In sharp contrast is dualism, a theory of mind famously put forth by Rene Descartes in the 17th century when he claimed that ?there is a great difference between mind and body, inasmuch as body is by nature always divisible, and the mind is entirely indivisible? the mind or soul of man is entirely different from the body.? In the proceeding centuries, the notion of the disembodied mind flourished. From it, western thought developed two basic ideas: reason is disembodied because the mind is disembodied and reason is transcendent and universal. However, as George Lakoff and Rafeal N??ez explain:

Cognitive science calls this entire philosophical worldview into serious question on empirical grounds? [the mind] arises from the nature of our brains, bodies, and bodily experiences. This is not just the innocuous and obvious claim that we need a body to reason; rather, it is the striking claim that the very structure of reason itself comes from the details of our embodiment? Thus, to understand reason we must understand the details of our visual system, our motor system, and the general mechanism of neural binding.

What exactly does this mean? It means that our cognition isn?t confined to our cortices. That is, our cognition is influenced, perhaps determined by, our experiences in the physical world. This is why we say that something is ?over our heads? to express the idea that we do not understand; we are drawing upon the physical inability to not see something over our heads and the mental feeling of uncertainty. Or why we understand warmth with affection; as infants and children the subjective judgment of affection almost always corresponded with the sensation of warmth, thus giving way to metaphors such as ?I?m warming up to her.?

Embodied cognition has a relatively short history. Its intellectual roots date back to early 20th century philosophers Martin Heidegger, Maurice Merleau-Ponty and John Dewey and it has only been studied empirically in the last few decades. One of the key figures to empirically study embodiment is University of California at Berkeley professor George Lakoff.

Noam Chomsky (Wikimedia Commons)

Lakoff was kind enough to field some questions over a recent phone conversation, where I learned about his interesting history first hand. After taking linguistic courses in the 1960s under Chomsky at MIT, where he eventually majored in English and Mathematics, he studied linguistics in grad school at Indiana University. It was a different world back then, he explained, ?it was the beginning of computer science and A.I and the idea that thought could be described with formal logic dominated much of philosophical thinking. Turing machines were popular discussion topics, and the brain was widely understood as a digital computational device.? Essentially, the mind was thought of as a computer program separate from the body with the brain as general-purpose hardware.

Chomsky?s theory of language as a series of meaningless symbols fit this paradigm. It was a view of language in which grammar was independent of meaning or communication. In contrast, Lakoff found examples showing that grammar was depended of meaning in 1963. From this observation he constructed a theory called Generative Semantics, which was also disembodied, where logical structures were built into grammar itself.

To be sure, cognitive scientists weren?t dualists like Descartes ? they didn?t actually believe that the mind was physically separate from the body ? but they didn?t think that the body influenced cognition. And it was during this time ? throughout the 60s and 70s -Lakoff realized the flaws of thinking about the mind as a computer and began studying embodiment.

The tipping point came after attending four talks that hinted at embodied language at Berkeley in the summer of 1975. In his words, they forced him to ?give up and rethink linguistics and the brain.? This prompted him and a group of colleagues to start cognitive linguistics, which contrary to Chomskyan theory and the entire mind as a computer paradigm, held that ?semantics arose from the nature of the body.? Then, in 1978, he ?discovered that we think metaphorically,? and spent the next year gathering as many metaphors as he could find.

Many cognitive scientists accepted his work on metaphors though it opposed much of mainstream thought in philosophy and linguistics. He caught a break on January 2nd 1979, when he got a call from Mark Johnson, who informed him that he was coming to Berkeley to replace someone in the philosophy department for six months. Johnson had just gotten his PhD from Chicago where he studied continental philosophy and called Lakoff to see if he was interested in studying metaphors. What came next was one of the more groundbreaking books in cognitive science. After co-writing a paper for the journal of philosophy in the spring of 1979, Lakoff and Johnson began working on Metaphors We Live By, and managed to finish it three months later.

Their book extensively examined how, when and why we use metaphors. Here are a few examples. We understand control as being UP and being subject to control as being DOWN: We say, ?I have control over him,? ?I am on top of the situation,? ?He?s at the height of his power,? and, ?He ranks above me in strength,? ?He is under my control,? and ?His power is on the decline.? Similarly, we describe love as being a physical force: ?I could feel the electricity between us,? ?There were sparks,? and ?They gravitated to each other immediately.? Some of their examples reflected embodied experience. For example, Happy is Up and Sad is Down, as in ?I?m feeling up today,? and ?I?m feel down in the dumbs.? These metaphors are based on the physiology of emotions, which researchers such as Paul Eckman have discovered. It?s no surprise, then, that around the world, people who are happy tend to smile and perk up while people who are sad tend to droop.

Metaphors We Live By was a game changer. Not only did it illustrate how prevalent metaphors are in everyday language, it also suggested that a lot of the major tenets of western thought, including the idea that reason is conscious and passionless and that language is separate from the body aside from the organs of speech and hearing, were incorrect. In brief, it demonstrated that ?our ordinary conceptual system, in terms of which we both think and act, is fundamentally metaphorical in nature.?

David - brain (Wikimedia Commons)

After Metaphors We Live By was published, embodiment slowly gained momentum in academia. In the 1990s dissertations by Christopher Johnson, Joseph Grady and Srini Narayanan led to a neural theory of primary metaphors. They argued that much of our language comes from physical interactions during the first several years of life, as the Affection is Warmth metaphor illustrated. There are many other examples; we equate up with control and down with being controlled because stronger people and objects tend to control us, and we understand anger metaphorically in terms of heat pressure and loss of physical control because when we are angry our physiology changes e.g., skin temperature increases, heart beat rises and physical control becomes more difficult.

This and other work prompted Lakoff and Johnson to publish Philosophy in the Flesh, a six hundred-page giant that challenges the foundations of western philosophy by discussing whole systems of embodied metaphors in great detail and furthermore arguing that philosophical theories themselves are constructed metaphorically. Specifically, they argued that the mind is inherently embodied, thought is mostly unconscious and abstract concepts are largely metaphorical. What?s left is the idea that reason is not based on abstract laws because cognition is grounded in bodily experience (A few years later Lakoff teamed with Rafael N??ez to publish Where Mathematics Comes From to argue at great length that higher mathematics is also grounded in the body and embodied metaphorical thought).

As Lakoff points out, metaphors are more than mere language and literary devices, they are conceptual in nature and represented physically in the brain. As a result, such metaphorical brain circuitry can affect behavior. For example, in a study done by Yale psychologist John Bargh, participants holding warm as opposed to cold cups of coffee were more likely to judge a confederate as trustworthy after only a brief interaction. Similarly, at the University of Toronto, ?subjects were asked to remember a time when they were either socially accepted or socially snubbed. Those with warm memories of acceptance judged the room to be 5 degrees warmer on the average than those who remembered being coldly snubbed. Another effect of Affection Is Warmth.? This means that we both physically and literary ?warm up? to people.

The last few years have seen many complementary studies, all of which are grounded in primary experiences:

? Thinking about the future caused participants to lean slightly forward while thinking about the past caused participants to lean slightly backwards. Future is Ahead

? Squeezing a soft ball influenced subjects to perceive gender neutral faces as female while squeezing a hard ball influenced subjects to perceive gender neutral faces as male. Female is Soft

? Those who held heavier clipboards judged currencies to be more valuable and their opinions and leaders to be more important. Important is Heavy.

? Subjects asked to think about a moral transgression like adultery or cheating on a test were more likely to request an antiseptic cloth after the experiment than those who had thought about good deeds. Morality is Purity

Studies like these confirm Lakoff?s initial hunch ? that our rationality is greatly influenced by our bodies in large part via an extensive system of metaphorical thought. How will the observation that ideas are shaped by the body help us to better understand the brain in the future?

I also spoke with Term Assistant Professor of Psychology Joshua Davis, who teaches at Barnard College and focuses on embodiment. I asked Davis what the future of embodiment studies looks like (he is relatively new to the game, having received his PhD in 2008). He explained to me that although ?a lot of the ideas of embodiment have been around for a few decades, they?ve hit a critical mass? whereas sensory inputs and motor outputs were secondary, we now see them as integral to cognitive processes.? This is not to deny computational theories, or even behaviorism, as Davis said, ?behaviorism and computational theories will still be valuable,? but, ?I see embodiment as a new paradigm that we are shifting towards.?

What exactly will this paradigm look like? It?s unclear. But I was excited to hear from Lakoff that he is trying to ?bring together neuroscience with the neural theory of language and thought,? through a new brain language and thought center at Berkeley. Hopefully his work there, along with the work of young professors like Davis, will allow us to understand the brain as part of a much greater dynamic system that isn?t confined to our cortices.

The author would like to personally thank Professors Lakoff and Davis for their time, thoughts, and insights. It was a real pleasure.

Source: http://rss.sciam.com/click.phdo?i=4d698bbcfe0b06e9a041d129688327fc

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