If you have had Cymbalta (common name: duloxetine) prescribed by your doctor, and are now stopping or tapering the medicine, there are a number of things with which you should be familiar so you know what to expect from withdrawal from Cymbalta. Duloxetine is an SNRI (a serotonin-norepinephrine re-uptake inhibitor) and as such, it shares many withdrawal cravings with other drugs in this class. Selective serotonin re-uptake suppressants (SSRIs) are also associated with similar withdrawal issues, and so these sorts of experiences generally have been termed ?antidepressant discontinuation syndrome?.
If your healthcare provider has decided that a different drug or dosage would be better suited for you, he has most probably suggested a slow tapering of duloxetine till you stop it altogether. In medical trials, up to half of people have experienced complications of differing intensity after sudden termination of duloxetine. A method to avoid this is by the tapering methodology, which slowly gets the body used to the reduced amounts of the medicine in the brain. Nonetheless this technique does not completely prevent the occurrence of complications and withdrawal.
Antidepressant discontinuation syndrome includes both physical and psychological elements. In terms of physical symptoms, you can experience dizziness, revulsion, headaches, tingling or burning sensations, gut issues including barfing, or nightmares. It is really important to notice that these experiences typically take place in about 1 in 20 folks, though dizziness is more common (around 1 in 10). One of the more tricky physical side effects has been named the ?brain zaps? or ?brain shivers? by people who have experienced it. They describe a sensation, that may arise when the head is suddenly turned, like a pressure drop accompanied by a ?zap? in the ears, together with a sense of dislocation like floating.
In terms of mental effects, withdrawal from duloxetine may result in irritability, and because of the lack of mood suppressant medicine, depressive symptoms are probably going to occur.
Onset of withdrawal problems may happen up to a week following reduced dose, and symptoms may last from a few days to two weeks. It is important to note that most peoples symptoms are mild, and they resolve themselves over a period of time. If symptoms are too harsh, your physician may put you back on the drug temporarily, and begin a slower tapering.
Doug Graham received his postgraduate training in psychology from UTSW Clinic in Dallas. He enjoys training the general public about getting off Cymbalta and other anti-depression treatments, like Suboxone.
Source: http://newhealthandfitness.org/2012/02/01/what-can-be-expected-from-withdrawal-from-cymbalta/
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